Citation Information :
Gupta T, Sadna G, Aggarwal N. Lesion Sterilization and Tissue Repair—A Recent Novel Approach for the Treatment of Very Uncooperative Pediatric Patients. Curr Trends Diagn Treat 2018; 2 (1):50-53.
Introduction: Root canal complexities of deciduous teeth often makes the treatment difficult and makes the child patient uncooperative and sometimes leads to treatment failure. Therefore the noninvasive approach is needed to obtain good cooperation from child patient.
Aim: This case report aimed to evaluate the use of triple antibiotic paste clinically-a combination of antibacterial drugs, i.e., metronidazole, minocycline, and ciprofloxacin (3Mix), and propylene glycol as pulp medicament on a necrosed primary molar.
Case description: Two children reported with necrosed primary molar and dentoalveolar abscess were treated with lesion sterilization and tissue repair (LSTR) therapy. The triple antibiotic paste was placed in the access cavity and then sealed with glass-ionomer cement. Subjects were asked for recall visits post-treatment, for clinical and radiographic evaluation.
Conclusion: The study revealed that LSTR treatment showed clinical and radiographic positive response on necrosed primary molars in an uncooperative patient.
Jaya AR, Praveen P, Anantharaj A, Venkataraghavan K, Rani PS. In vivo evaluation of lesion sterilization and tissue repair in primary teeth pulp therapy using two antibiotic drug combinations. J ClinPediatr Dent. 2012 Winter;37(2):189-191.
Burrus D, Barbeau L, Hodgson B. Treatment of abscessed primary molars utilizing lesion sterilization and tissue repair: literature review and report of three cases. Pediatr Dent. 2014 May-Jun;36(3):240-244.
Trairatvorakul C, Detsomboonrat P. Success rates of a mixture of ciprofloxacin, metronidazole, and minocycline antibiotics used in the non-instrumentation endodontic treatment of mandibular primary molars with carious pulpal involvement. Int J Paediatr Dent. 2012 May;22(3):217-227.
Takushige T, Cruz Ev, Moral A, Hoshino E. Endodontic Treatment of primary teeth using combination of antibacterial drugs. IntEndod J. 2004;37:132-138.
Sato I, Ando-Kurihara N, Kota K, et al. Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. IntEndod J. 1996;29(2):118-124.
Cruz EV, Kota K, Huque J, Iwaku M, Hoshino E. Penetration of propylene glycol into dentine. IntEndod Journal. 2002;35:330- 336.
Rocha MJ, Cardoso M, Endodontic treatment of traumatized primary teeth – Part2. Dent. Traumatol. 2004;20(6):314-326.
Hoshino E, Asgor MA, Yagi M, Garcia MCG, Cruz EV, Oyanagi H, Kota K. Oral Health program using LSTR 3 Mix- MP NIET Therapy: Pulp Cell Behaviour: Pulp Therapy and Endod. 2006;1786.
Silistreli OK, Durmus EU, Ulusal BG, et al. What should be the treatment modality in giant cutaneous lipomas? Review of the literature and report of 4 cases. Br J PlastSurg 2005;58:394-398.
Li YF, et al. Giant lipoma of the breast: a case report and review of the literature. Clin Breast Cancer, Cancer 2011;11(6):420-422.
Ribeiro RC, Saltz R, Espana Quintera LF. Breast reconstruction with parenchymal cross after giant lipoma removal. Aesthetic Plast Surg. 2008 Jul:32(4):695–697.
Tuncel M, Maral T, Celik H, Tasçioglu B. A case of bilateral anomalous origin for dorsalis pedis arteries (anomalous dorsalis pedis arteries). Surg Radiol Anat. 1994;16:319-323.
Plecha EL, Seabgook GR, Bandyk DF, Towne JB. Determinants of successful peroneal artery bypass. J Vasc Surg. 1993; 17: 97-105.
Senior HD. The development of the arteries of the human lower extremity. Am J Anat. 1919;25(1):54-95.
Atanasova M, Georgiev GP, Jelev L. Intriguing variations of the tibial arteries and their clinical implications. Int J Anat Var. 2011;4:45-47.
Fedorov VB, Goropashnaya AV, Ø.Tøien et al., “Preservation of bone mass and structure in hibernating black bears (Ursus americanus) through elevated expression of anabolic genes,” Functional and Integrative Genomics. 2012;12(2):357-365.
Chow BA, Donahue SW, Vaughan MR, McConkey B, Vijayan MM, “Serum immune-related proteins are differentially expressed during hibernation in theAmerican black bear,” PLoS ONE. 2013;8(6).
Virginia B. A Tale of Two Colonies: What Really Happened in Virginia and Bermuda? University of Missouri Press 2011. ISBN 0826272576 pp. 112.
Bydlowska J. Drunk Mom: A Memoir. Doubleday Canada. Penguin Random House publications 2013 ISBN 0385677812 pp. 91.
Pojman P, Pojman L. Food Ethics. Cengage Learning US. Wadsworth Publishing 2011. pp. 128. ISBN 1111772304.
With spirulina, and togethers, we will end child malnutrition in the world Now.” Available from http://www.indiegogo. com/projects/with- spirulina-and-togethers-we-will-endchild- malnutrition-in-the-world-now. Retrieved Dec 16, 2014.
Lucas A, “Programming by early nutrition in man,” in The Childhood Environment and Adult Disease, G. R. Bock and J. Whelan, Eds., Ciba Foundation Symposium 156, JohnWiley & Sons, Chichester, UK, 1991 pp. 38-55.
McCance RA, Widdowson EM. “The determinants of growth and form,” Proceedings of the Royal Society of London B— Biological Sciences 1974;185(1078):1-17.
Hermanussen M, M de Los Angeles Roi de Lama, Romero AP, Ruiz CA, Burmeister J, Tresguerres JAF. “Differential catch-up in body weight and bone growth after short-term starvation in rats,” Growth Regulation 1996;6(4):230-237.
Banu MJ, Orhii PB, Mejia W et al.“Analysis of the effects of growth hormone, voluntary exercise, and food restriction on diaphyseal bone in female F344 rats,”Bone. 1999; 25(4):469-480.
Banu J, Orhii PB, Okafor MC, Wang L, Kalu DN. “Analysis of the effects of growth hormone, exercise and food on diaphyseal bone in female F344 rats,” Bone 1999; 25(4): 469-480.
Janiszewski P. Obesity Panacea – [News nutrition, peer reviewed research]:[Janiszewski]; [may 13, 2011] - The Science of Starvation: How long can humans survive without food or water?Available from http://blogs.plos.org/obesitypanacea/ about this blog.
Beresford D. Ten Men Dead. New York: Atlantic Press. 1997. ISBN 0-87113-702-X.
Srimat Bhagvatam. SB 4.8.71 - SB 4.8.79
Attia E. “Anorexia nervosa: current status and future directions,”Annual Review of Medicine 2010;61(1) 425-435.
Rosen JC, Reiter J, and Orosan P, “Assessment of body image in eating disorders with the body dysmorphic disorder examination,” Behaviour Research and Therapy 1995; 33(1):77–84.
Grinspoon S, Miller K, Coyle C et al., “Severity of osteopenia in estrogen-deficient women with anorexia nervosa and hypothalamic amenorrhea,” Journal of Clinical Endocrinology and Metabolism 1999;84(6):2049-2055.
Biller BMK, Saxe V, Herzog D.B., Rosenthal DI, Holzman S, Klibanski A. “Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa,” Journal of Clinical Endocrinology and Metabolism 1989; 68(3): 548-554.
Grinspoon S, Thomas E, Pitts S et al., “Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa,” Annals of Internal Medicine 2000;133(10): 790-I42.
Rigotti NA, Neer RM, Skates SJ, Herzog DB, Nussbaum SR, “The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass,” The Journal of the American Medical Association 1991;265(9): 1133-1138.
Baker D, Roberts R, Towell T, “Factors predictive of bone mineral density in eating-disordered women: a longitudinal study,” International Journal of Eating Disorders 2000;27(1): 29-35.
Khosla S, Lufkin EG, Hodgson SF, Fitzpatrick LA, Melton LJ III, “Epidemiology and clinical features of osteoporosis in younindividuals,” Bone 1994;15(5):551-555.
Zipfel S, Seibel MJ, Löwe B, Beumont PJ, Kasperk C, Herzog W. “Osteoporosis in eating disorders: a follow-up study of patients with anorexia and bulimia nervosa,” Journal of Clinical Endocrinology and Metabolism 2001;86(11):5227–5233.
Soyka LA, Grinspoon S, Levitsky LL, Herzog DB, Klibanski A. “The effects of anorexia nervosa on bone metabolism in female adolescents,” Journal of Clinical Endocrinology and Metabolism 1999;84(12):4489-4496.
LA Soyka, M. Misra, A. Frenchman et al., “Abnormal bone mineral accrual in adolescent girls with anorexia nervosa,”Journal of Clinical Endocrinology and Metabolism 2002; 87(9):4177-4185.
MM LaBan, JC Wilkins, AH Sackeyfio, and RS Taylor, “Osteoporotic stress fractures in anorexia nervosa: etiology, diagnosis, and review of four cases,” Archives of Physical Medicine and Rehabilitation 1995;76(9):884-887.
Y Maugars, J.-M. Berthelot, S. Lalande, C. Charlier, and A. Prost, “Osteoporotic fractures revealing anorexia nervosa in five females,” Revue du Rhumatisme (English Edition) 1996; 63(3):201–206.
Golden NH et al. Resumption of Menses in Anorexia Nervosa. Arch Pediatr Adolesc med 1997;151:16-21.
Audi L et al. Leptin in Relation to Resumption of Menses in Women with Anorexia Nervosa. Mol Psychiatry 1998;4:544-547.
Mehanna HM, Moledina J, Travis J. “Refeeding syndrome: what it is, and how to prevent and treat it”. BMJ 2008; 336: 1495 8. doi:10.1136/bmj.a301.PMC 2440847. PMID 18583681.
“The Physiology and Treatment of Starvation”. US national library of medicine. Retrieved 17 August 2012. chromeextension://mhjfbmdgcfjbbpaeojofohoefgiehjai/index.html
Kreipe R et al. Eating Disorders in Adolescents and Older Children. Pediatrics in Review 1999; 20:12.
Pike KM et al. Cognitive Behavior Therapy in the Posthospitalization. Treatment of Anorexia Nervosa. Am J Pyschiatry 2004; 11:2046-2049.
Bender DA. Carbohydrates of Physiologic Significance. Murray RK, Bender DA, Botham KM, Kenelly PJ, Rodwell VW, Weil PA.. Harpers Illustrated Biochemistry 28th ed. New York:Mc Graw Hill publications; 2009. p 113-120.
Koffler M, Kisch ES. Starvation diet and very-low-calorie diets may Induce insulin resistance and overt diabetes mellitus. J Diabetes Complications.1996;10(2):109-12.
Hales CN, Barker DJ The thrifty phenotype hypothesis. Br Med Bull. 2001;60:5-20.
Hales CN, Barker DJ (July 1992). “Type 2 (non-insulindependent) diabetes mellitus: the thrifty phenotype hypothesis”. Diabetologia. 35 (7): 595-601.
Barker, D.J.P. (1997). “Maternal Nutrition, Fetal Nutrition, and Disease in Later Life”. Nutrition, ‘13’, pp. 807.
Martin, Paul; Bateson, Patrick (1999). Design for a life: How behaviour develops. London: Jonathan Cape. ISBN 0-224- 05064-8 pp. 110-111.
Barker, DJP. ed. (1992). Fetal and infant origins of adult disease. London: British Medical Journal. ISBN 0-7279-0743-3.
Robinson R (February 2001). “The fetal origins of adult disease: No longer just a hypothesis and may be critically important in south Asia”. Editorial
Mazur A. Why were “starvation diets” promoted for diabetes in the pre-insulin period? Nutrition Journal 2011;10:23.
Goodacre CJ, Kan JY, Rungcharassaeng K. Clinical complications of osseointegrated implants. J Prosthet Dent 1999 May;81(5):537-552.
Evans CD, Chen ST. Esthetic outcomes of immediate implant placements. Clin Oral Implants Res 2008 Jan;19(1):73-80.
Romeo E, Lops D, Rossi A, Storelli S, Rozza R, Chiapasco M. Surgical and prosthetic management of interproximal region with single-implant restorations: 1-year prospective study. J Periodontol 2008 Jun;79(6):1048-1055.
Nagaraj KR, Savadi CR, Savadi AR, Prashanth Reddy GT, Srilakshmi J, Dayalan M, John J. Gingival biotype— prosthodontic perspective. J Indian Prosthodont Soc 2010 Mar;10(1):27-30.
Jung RE, Sailer I, Hämmerle CH, Attin T, Schmidlin P. In vitro color changes of soft tissues caused by restorative materials. Int J Periodontics Restorative Dent 2007 Jun;27(3): 251-257.