Citation Information :
Kaur A, Chawla A, Manjari M. Incidence and Clinicopathological Correlation of Cervical Cancer in a Tertiary Care Center: A 5-year Retrospective Study. Curr Trends Diagn Treat 2019; 3 (2):64-67.
Introduction: Cervical carcinoma is the second most common cancer of women in India, with the first being breast carcinoma. In 2018, the age standardized incidence rate in the world was 13.1% and in India was14.7%, with 569,847 new cases and 311,365 deaths in 2018 in the world. Infection by human papillomavirus (HPV) is the most common risk factor for cervical cancer, with more than 99% cases expressing viral sequence. The present study was undertaken to study the incidence, various clinical presentations, and the histological types of cervical carcinoma. Materials and methods: The study was carried out in a tertiary care center for a period of 5 years (January 2015 to December 2019) on histopathologically diagnosed cases of cervical cancer. A total of 308 cases of cervical carcinoma were studied in this period. Results: Incidence of cervical cancer in the present study was 2.9%. Maximum number of cases was seen in fifth and sixth decades. The most common clinical presentation was postmenopausal bleeding (78.6%) followed by discharge per vaginam (66.6%). On microscopy, squamous cell carcinoma (SCC)-large-cell nonkeratinizing type was most common (89%) followed by adenocarcinoma (5.5%). Other types were adenosquamous (1.9%) and small cell carcinoma (1.9%), and the least common was SCC-large-cell keratinizing type (1.6%). Of the 308 cases, 164 (53.2%) were in stage II followed by 95 cases (30.2%) in stage I. Conclusion: In conclusion, the current study stressed the fact that as a majority of Indian women are diagnosed at later stages of cervical cancer rather than in its early treatable stages, so there is a need for strengthening and proper implementation of screening programs. Keeping in mind the incidence, the knowledge of vaccination against HPV for prevention of carcinoma cervix should also be followed.
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