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VOLUME 5 , ISSUE 2 ( July-December, 2021 ) > List of Articles

CASE REPORT

Acute Dengue Myositis: A Case Report

Manavdeep Kaur, Parminder Singh

Keywords : Creatine kinase, Flavivirus, Myositis

Citation Information : Kaur M, Singh P. Acute Dengue Myositis: A Case Report. Curr Trends Diagn Treat 2021; 5 (2):102-103.

DOI: 10.5005/jp-journals-10055-0125

License: CC BY-NC 4.0

Published Online: 01-04-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Dengue is an arthropod-borne viral infection caused by genus flavivirus. The most important flaviviruses that cause fever and myalgia syndrome are dengue viruses 1–4. Dengue viral infection causes many complications such as pneumonia, bone marrow failure, hepatitis, retinal hemorrhages, maculopathy, and myositis. Neurologic complications such as encephalitis, Guillain–Barre syndrome, phrenic neuropathy, subdural hematoma, and cerebral vasculitis are less common. Limited case series have indicated the possibility of skeletal muscle invasion causing myositis. We present a case of a 54-year-old male who presented with high-grade fever and muscular pain in both upper and lower limbs. His serum creatine kinase (CPK) value was 619 U/L. He was managed conservatively and low-dose corticosteroids were given. Our case highlights the severe muscle involvement in dengue infection which is a rare entity.


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  1. Solomon T, Dung NM, Vaughn DW, et al. Neurological manifestations of dengue infection. Lancet 2000;355(9209):1053–1059. DOI: 10.1016/S0140-6736(00)02036-5.
  2. Miagostovich MP, Ramos RG, Nicol AF, et al. Retrospective study on dengue fatal cases. Clin Neuropathol 1997;16(4):204–208. PMID: 9266146.
  3. Warke RV, Becerra A, Zawadzka A, et al. Efficient dengue virus (DENV) infection of human muscle satellite cells upregulates type I interferon response genes and differentially modulates MHC I expression on bystander and DENV-infected cells. J Gen Virol 2008;89:1605–1615. DOI: 10.1099/vir.0.2008/000968-0.
  4. Mishra UK, Kalita J. Spectrum of neurological manifestations of dengue in India. Dengue Bull 2006;30:107–113.
  5. Beauvais P, Quinet B, Richardet JM. Dengue apoptosis of two cases. Arch Fr Pediatr 1993;50(10):905–907. PMID: 8053773.
  6. George R, Liam CK, Chua CT, et al. Unusual clinical manifestations of dengue virus infection. Southeast Asian J Trop Med Public Health 1988;19(4):585–590. PMID: 3238469.
  7. Davis JS, Bourke P. Rhabdomyolysis associated with dengue virus infection. Clin Infect Dis 2004;38(10):e109–e111. DOI: 10.1086/392510.
  8. Finsterer J, Kongchan K. Severe, persisting, steroid responsive Dengue myositis. J Clin Virol 2006;35(4):426–428. DOI: 10.1016/j.jcv.2005.11.010.
  9. Said SM, Elsaeed KM, Zakareya A. Benign acute myositis in association with acute dengue viruses infections. Egypt J Neurol Psychiat Neurosurg 2008;45(1):193–200.
  10. Karakus A, Banga N, Voorn GP, et al. Dengue shock syndrome and rhabdomyolysis. Neth J Med 2007;65(2):78–81. PMID: 17379934.
  11. Gagnon SJ, Mori M, Kurane I, et al. Cytokine gene expression and protein production in peripheral blood mononuclear cells of children with acute dengue virus infections. J Med Virol 2002;67(1):41–46. DOI: 10.1002/jmv.2190.
  12. Gulati K, Pasi R, Gupta A, et al. Dengue fever presenting with severe myositis—an unusual presentation. J Family Med Prim Care 2020;9(12):6285–6287. DOI: 10.4103/jfmpc.jfmpc_1680_20.
  13. Malheiros SM, Oliveira AS, Schmidt B, et al. Dengue. Muscle biopsy findings in 15 patients. Arq Neuropsiquiatr 1993;51(2):159–164. DOI: 10.1590/s0004-282x1993000200001.
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