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VOLUME 5 , ISSUE 2 ( July-December, 2021 ) > List of Articles


Sensory Chronic Inflammatory Demyelinating Polyneuropathy—A Variant of Chronic Inflammatory Demyelinating Polyneuropathy: A Rare Case Report

Sanjeev K Saggar, Kawalinder K Girgla

Keywords : Chronic inflammatory demyelinating polyneuropathy (CIDP), Compound muscle action potential (CMAP), Guillain-Barre syndrome (GBS), Nerve conduction studies (NCS), Sensory nerve action potential (SNAP)

Citation Information : Saggar SK, Girgla KK. Sensory Chronic Inflammatory Demyelinating Polyneuropathy—A Variant of Chronic Inflammatory Demyelinating Polyneuropathy: A Rare Case Report. Curr Trends Diagn Treat 2021; 5 (2):114-115.

DOI: 10.5005/jp-journals-10055-0135

License: CC BY-NC 4.0

Published Online: 08-12-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Background: Chronic inflammatory demyelinating polyneuropathy (CIDP) is progressive, sometimes relapsing disorder of peripheral nerves. It usually develops over months or years. Abrupt onset resembling Guillain-Barre syndrome (GBS) can occur and symptoms can persist. Pure sensory form of CIDP is rare and visualized in just 5% patients of CIDP. Case description: A 44-year-old female presented to emergency department with a 12-month history of progressively worsening numbness in hands, feet, and extreme weakness. She had decreased pin prick and touch sensation in a stocking-glove distribution. Patient's history and nerve conduction study were indicative of sensory variant of CIDP. Discussion: In patients who exhibit pure sensory form of CIDP, clinically sensory deficit predominantly manifests. Moreover, there is decrease in amplitude of sensory nerve action potential (SNAP) in case of sensory nerve, i.e., sural nerve, median sensory nerve, etc. In a given case, nerve conduction studies showed more than 50% decrease in SNAP. A significant decrease in amplitude of SNAP with no motor nerve conduction abnormality is the requirement for the sensory variant of CIDP, which is a characteristic feature seen in the given case.

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