AMEI's Current Trends in Diagnosis & Treatment

Register      Login

VOLUME 2 , ISSUE 2 ( July-December, 2018 ) > List of Articles

CASE REPORT

Radiological and Imaging Findings in Gastrointestinal Stromal Tumor: A Case Report

Nilanshu Kataria, Vijinder Arora

Keywords : Contrast-enhanced CT, Gastrointestinal stromal tumor, Histopathology, Ultrasonography

Citation Information : Kataria N, Arora V. Radiological and Imaging Findings in Gastrointestinal Stromal Tumor: A Case Report. Curr Trends Diagn Treat 2018; 2 (2):112-114.

DOI: 10.5005/jp-journals-10055-0050

License: CC BY-NC 4.0

Published Online: 01-08-2011

Copyright Statement:  Copyright © 2018; The Author(s).


Abstract

Introduction: Gastrointestinal stromal tumors (GISTs) are nonepithelial tumors arising from the interstitial cells of Cajal, which express KIT protein-CD117 on immunohistochemistry. It represents a wide clinical spectrum of tumors with different clinical presentations, locations, histology, and prognosis. Gastro intestinal stromal tumours (GISTs) can arise anywhere in the GIT, including the mesentery, omentum, and retroperitoneum. Because most of these tumors are submucosal in location, they usually attain a large size without causing bowel obstruction at the time of diagnosis. This report presents a case of GIST in a 30-year-old male. The patient presented with acute abdomen without any symptoms of obstruction or perforation. He underwent ultrasonography in the radiology department which revealed a large mass along the small bowel with deposits along the mesentery and space occupying lesions (SOLs) in the liver. On contrast-enhanced computerised tomography (CECT), a possibility of GIST with deposits along the mesentery and liver was given, which was confirmed by histopathology. Conclusion: Recognition and acquaintance with GISTs is primarily important for early detection which allows for more treatment options. These tumors are rare in people younger than 40 years of age, but can occur in people of any age.


HTML PDF Share
  1. George S, Desai J. Management of gastrointestinal stromal tumors in the era of tyrosine kinase inhibitors. Curr Treat Options Oncol 2002;3:489-496.
  2. Miettinen M, Virolainen M, Maarit Sarlomo R. Gastrointestinal stromal tumors-value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol 1995;19:207-216.
  3. Miettinen M, Lasota J. Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001;438:1-12.
  4. Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998;279:577-580.
  5. Levy AD, Remotti HE, Thompson WM, et al. Gastrointestinal stromal tumors: radiologic features with pathologic correlation. Radiographics 2003;23:283-304.
  6. Chun HJ, Byun JY, Chun KA, et al. Gastrointestinal leiomyoma and leiomyosarcoma: CT differentiation. J Comput Assist Tomogr 1998;22:69-74.
  7. Sandrasegaran K, Rajesh A, Rushing DA, et al. Gastrointestinal stromal tumors: CT and MRI findings. Eur Radiol 2005;15: 1407-1414.
  8. Rha SE, Ha HK, Kim AY, et al. Peritoneal leiomyosarcomatosis originating from gastrointestinal leiomyosarcomas: CT features. Radiology 2003;227:385-390.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.