Aim and objective: To study the effects of obesity on the pulmonary functions in male medical students of Amritsar.
Materials and methods: Pulmonary function tests (PFTs) of normal, healthy, male medical students of Amritsar were determined and were compared and correlated with other studies. Criteria for obesity in our study taken were according to WHO criteria of BMI. The PFTs were carried out with a computerized spirometer “Med-Spiror”. The data were collected; compiled, statistically analyzed, and valid conclusions were drawn. Higher lung volumes and flow rates were achieved.
Results: There was a statistically highly significant decline in forced vital capacity (FVC) in obese when compared with nonobese groups. The values of forced expiratory volume in first second (FEV1) in both groups when were compared showed significant changes. The ratio of FEV1/FVC, the values of peak expiratory flow rate (PEFR), and forced mid-expiratory flow (FEF25–75%) showed insignificant changes but maximum voluntary ventilation (MVV) when were compared showed highly significant changes.
Conclusion: There is a decline of various respiratory functions in obesity. The cause of the decline of various respiratory functions in obesity may be due to a decrease in distensibility of the chest wall or limited expansion of the thoracic cavity and is the cause for reduced ventilatory volumes and total lung capacity.
Sharma VK, Garg VK, Parihar HL, et al. Respiratory morbidity and pulmonary function impairment in ‘soldiers’: an occupational hazard in modern electronics. Lung India 1993;11(4):143–146.
Singh SK, Nishith DS, Tandon GS, et al. Some observations of pulmonary function tests in rice mill workers. Indian J Physiol Pharmacol 1988;32(2):152–157.
Kharodi C, Goel A, Puri N, et al. Correlation of body mass index with pulmonary function tests in North Indian females. Int J Contemp Med Res 2019;6(3):C10–C12. DOI: 10.21276/ijcmr.2019.6.3.36.
NHANES Data on the Prevalence of overweight and obesity among Adults: United States; 2003–2004.
Chaudhary SC, Kumari T, Usman K, et al. Study of pulmonary function test abnormalities in metabolic syndrome. J Assoc Physicians India 2018;66(10):27–30.
Koenig SM. Pulmonary complications of obesity: a review. Am J Med Sci 2001;321(4):249–279.
Yeh F, Dixon AE, Marion S, et al. Obesity in adults is associated with reduced lung function in metabolic syndrome and diabetes: the Strong Heart Study. Diabetes Care 2011;34(10):2306–2313. DOI: 10.2337/dc11-0682.
Marcus CL, Curtis S, Koerner CB. Evaluation of pulmonary function and polysomnography in obese children and adolescents. Pediatr Pulmol 1996;21(3):176–183. DOI: 10.1002/(SICI)1099-0496(199603)21:3<176::AID-PPUL5>3.0.CO;2-O.
WHO (1998). Technical Report Series 894. Obesity: preventing and managing the global epidemic. http://www.who.int/nutrition/publications/obesity/WHO_TRS_894/en/index.html. Accessed on 04 Sep 2020.
WHO (2000). World Health Organization. Regional Office for the Western Pacific. (2000). The Asia-Pacific perspective: redefining obesity and its treatment. Sydney: Health Communications Australia. https://apps.who.int/iris/handle/10665/206936. Accessed on 04 Sep 2020.
Snehalatha C, Viswanathan V, Ramachandran A. Cutoff values for normal anthropometric variables in Asian Indian adults. Diabetes Care 2003;26(5):1380–1384. DOI: 10.2337/diacare.26.5.1380.
Cotes JE. Lung function assessment and application in medicine, 4th ed. London; Blackwell Scientific Publishers; 1979. pp. 332–345.
Oriel EJ, Vasavada JP, Khanijo SK, et al. Observations on pulmonary functions in obesity. Indian J Chest Dis Allied Sci 1979;21(2): 73–79.
Hatem AM, Ismail MS, El-Hinnawy YH. Effect of different classes of obesity on the pulmonary functions among adult Egyptians: a cross-sectional study. Egypt J Bronchol 2019;13(4):510–515. DOI: 10.4103/ejb.ejb_21_19.
Wang S, Sun X, Hsia T, et al. The effects of body mass index on spirometry tests among adults in Xi'an, China. Medicine 2017;96(15):e6596. DOI: 10.1097/MD.0000000000006596.
Sorani A, Savalia C, Chavda B, et al. Analysis of lung functions in obese young adult male. Int J Basic Appl Physiol 2013;2(1):25–29.
Chen Y, Rennie D, Cormier YF, et al. Waist circumference is associate d with pulmonary function in normal-weight, overweight, and obese subjects. Am J Clin Nutr 2007;85(1):35–39. DOI: 10.1093/ajcn/85.1.35.
Lazarus R, Gore CJ, Booth M. Effects of body composition and fat distribution on ventilatory function in adults. Am J Clin Nutr 1998;68(1):35–41. DOI: 10.1093/ajcn/68.1.35.
Pankow W, Podszus T, Gutheil T. Expiratory flow limitation and intrinsic positive end expiratory pressure in obesity. J Appl Physiol 1998;85:1236–1243. DOI: 10.1152/jappl.19188.8.131.526.
Chinn DJ, Cotes JE, Reed JW. Longidutinal effects of change in body mass on measurements of ventilatory capacity. Thorax 1996;51:699–704. DOI: 10.1136/thx.51.7.699.
Bhattacharjee A, Malik T, Myat A, et al. Effect of obesity on pulmonary functions among the adolescent students of a private university in Malaysia. J Clin Diagn Res 2018;12(8):24–27. DOI: 10.7860/JCDR/2018/36228.12002.
Chen Y, Horne SL, Dosman JA. Body weight and weight gain related to pulmonary function decline in adults: a six year follow up study. Thorax 1993;48(4):375–380. DOI: 10.1136/thx.48.4.375.
Bottai M, Postello F, Fdi P, et al. Longitudinal changes of body mass index, spirometry and diffusion in a general population. Eur Respir J 2002;20:665–673. DOI: 10.1183/09031936.02.01282001.
Carey IM, Cook DC, Strachan DP. The effects of adiposity and weight change on forced expiratory volume decline in a longitudinal study of adults. Int J Obes Relat Metab Disord 1999;23(9):979–985. DOI: 10.1038/sj.ijo.0801029.
Biring MS, Lewis MI, Liv JT. Pulmonary physiological changes of morbid obesity. Am J Med Sci 1999;318:293–297. DOI: 10.1097/00000441-199911000-00002.
Ahmed D, Morgan WKC. Obesity and lung function. Thorax 2001;56(9):740–741. DOI: 10.1136/thorax.56.9.740c.
Zerah F, Harf A, Perlemuter L, et al. Effects of obesity on respiratory resistance. Chest 1993;103(5):1470–1476. DOI: 10.1378/chest.103.5.1470.
Ray CS, Sue DY, Bray G, et al. Effects of obesity on respiratory complication. Am Rev Respir Dis 1983;128(3):501–506. DOI: 10.1164/arrd.19184.108.40.2061.