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VOLUME 5 , ISSUE 2 ( July-December, 2021 ) > List of Articles

CASE REPORT

Sensory Chronic Inflammatory Demyelinating Polyneuropathy—A Variant of Chronic Inflammatory Demyelinating Polyneuropathy: A Rare Case Report

Sanjeev K Saggar, Kawalinder K Girgla

Keywords : Chronic inflammatory demyelinating polyneuropathy (CIDP), Compound muscle action potential (CMAP), Guillain-Barre syndrome (GBS), Nerve conduction studies (NCS), Sensory nerve action potential (SNAP)

Citation Information : Saggar SK, Girgla KK. Sensory Chronic Inflammatory Demyelinating Polyneuropathy—A Variant of Chronic Inflammatory Demyelinating Polyneuropathy: A Rare Case Report. Curr Trends Diagn Treat 2021; 5 (2):114-115.

DOI: 10.5005/jp-journals-10055-0135

License: CC BY-NC 4.0

Published Online: 01-04-2022

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Background: Chronic inflammatory demyelinating polyneuropathy (CIDP) is progressive, sometimes relapsing disorder of peripheral nerves. It usually develops over months or years. Abrupt onset resembling Guillain-Barre syndrome (GBS) can occur and symptoms can persist. Pure sensory form of CIDP is rare and visualized in just 5% patients of CIDP. Case description: A 44-year-old female presented to emergency department with a 12-month history of progressively worsening numbness in hands, feet, and extreme weakness. She had decreased pin prick and touch sensation in a stocking-glove distribution. Patient's history and nerve conduction study were indicative of sensory variant of CIDP. Discussion: In patients who exhibit pure sensory form of CIDP, clinically sensory deficit predominantly manifests. Moreover, there is decrease in amplitude of sensory nerve action potential (SNAP) in case of sensory nerve, i.e., sural nerve, median sensory nerve, etc. In a given case, nerve conduction studies showed more than 50% decrease in SNAP. A significant decrease in amplitude of SNAP with no motor nerve conduction abnormality is the requirement for the sensory variant of CIDP, which is a characteristic feature seen in the given case.


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  1. McCombe PA, Pollard JD, McLeod JG. Chronic inflammatory demyelinating polyradiculoneuropathy. A clinical and electrophysiological study of 92 cases. Brain 1987;110(Pt 6): 1617–1630. DOI: 10.1093/brain/110.6.1617.
  2. Mori K, Hattori N, Sugiura M, et al. Chronic inflammatory demyelinating polyneuropathy presenting with features of GBS. Neurology 2002;58(6):979–982. DOI: 10.1212/wnl.58.6.979.
  3. Oh SJ, Joy JL, Kuruoglu R. “Chronic sensory demyelinating neuropathy”: chronic inflammatory demyelinating polyneuropathy presenting as a pure sensory neuropathy. J Neurol Neurosurg Psychiatry 1992;5(8):677–680. DOI: 10.1136/jnnp.55.8.677.
  4. Sinnreich M, Klein CJ, Daube JR, et al. Chronic immune sensory polyradiculopathy: a possibly treatable sensory ataxia. Neurology 2004;63(9):1662–1669. DOI: 10.1212/01.WNL.0000142507.12763.58.
  5. Mishra UK, Kalita J. Clinical Neurophysiology. 3rd ed. New Delhi, India. Elsevier; 2014. p. 219.
  6. Busby M, Donaghy M. Chronic dysimmune neuropathy. A subclassification based upon the clinical features of 102 patients. J Neurol 2003;250(6):714–724. DOI: 10.1007/s00415-003-1068-2.
  7. van Dijk GW, Notermans NC, Franssen H, et al. Development of weakness in patients with chronic inflammatory demyelinating polyneuropathy and only sensory symptoms at presentation: a long-term follow-up study. J Neurol 1999;246(12):1134–1139. DOI: 10.1007/s004150050531.
  8. Rajabally YA, Wong SL. Chronic inflammatory pure sensory polyradiculoneuropathy: a rare CIDP variant with unusual electrophysiology. J Clin Neuromuscul Dis 2012;13(3):149–152. DOI: 10.1097/CND.0b013e31822484fb.
  9. Ayrignac X, Viala K, Koutlidis RM, et al. Sensory chronic inflammatory demyelinating polyneuropathy: an under-recognized entity? Muscle Nerve 2013;48(5):727–732. DOI: 10.1002/mus.23821.
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